Long-term efficacy and safety of galantamine in outpatients with mild cognitive disorder
نویسندگان
چکیده
Materials and methods A multicenter, open label, prospective, observational study enrolled 800 patients, more 50 years old with Mild Neurocognitive Disorder (DSM IV criteria), during 24 months of treatment with galantamine 16 mg./day. Assessments included the Mini Mental State Examination (MMSE), Clinical Dementia Rating (CDR), Alzheimer’s Disease Assessment Scale (ADAS-GOG), Seven minutes test, Wiscosin card sorting test, Boston naming test, Token test, Raven Test, Brow-Peterson test, Trail making test, Functional Activities Questionnaire (FAQ), GO-NO-GO test, Global Deterioration Scale, Global Clinical Impression (GCI) and UKU scale of Adverse Effects.
منابع مشابه
Long-term effect of galantamine on cognitive function in patients with Alzheimer’s disease versus a simulated disease trajectory: an observational study in the clinical setting
BACKGROUND Long-term maintenance of cognitive function is an important goal of treatment for Alzheimer's disease (AD), but evidence about the long-term efficacy of cholinesterase inhibitors is sparse. To evaluate the long-term efficacy and safety of galantamine for AD in routine clinical practice, we conducted a 72-week post-marketing surveillance study. The effect of galantamine on cognitive f...
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